How can I microdose with mushroom capsules? Experts prescribe that newbies use psilocybin capsules to microdose. When starting off your psilocybin journey, use a Microdose pill which contains 125mg of powdered dried psilocybin mushrooms. It is recommended that you keep you dose in this manner for as long as possible. https://homeofpsychedelics.quora.com/Psilocybin-Mushroom-Therapy-Denver-What-you-need-to-know